Good evening Daniel and welcome to the Events Calendar forum!
Thank you for your interest in our products.
We’ll be glad to answer your questions.
I.E. people will be creating websites in a WP Multisite network and would have access to manage events on their website. If we purchase the MS license can we use your plugin in this manner?
Yes. Absolutely.
Based on your description, that would totally work.
Depending on your needs, you might also want to take a look at our Community Events add-on that lets websites’ users contribute to the calendar from the front-end: https://theeventscalendar.com/product/wordpress-community-events/
Best regards,
Geoff B.