Hi,
Thanks for reaching out to us!
Sure, you can modifiy the layout of a single event page — you can refer to our Themer’s Guide to learn more about template customization.
The files you probably want to edit are located in wp-plugins/the-events-calendar/src/views/single-event.php and wp-plugins/the-events-calendar/src/views/modules/meta.php.
You can then override these templates in your own theme by creating a file respectively at [your-theme]/tribe-events/single-event.php and [your-theme]/tribe-events/modules/meta.php.
I hope this helps,
Cheers,
Jeremy